Rapid Bead-Based Antimicrobial Susceptibility Testing by Optical Diffusometry
نویسندگان
چکیده
منابع مشابه
Rapid Bead-Based Antimicrobial Susceptibility Testing by Optical Diffusometry.
This study combined optical diffusometry and bead-based immunoassays to develop a novel technique for quantifying the growth of specific microorganisms and achieving rapid AST. Diffusivity rises when live bacteria attach to particles, resulting in additional energy from motile microorganisms. However, when UV-sterilized (dead) bacteria attach to particles, diffusivity declines. The experimental...
متن کاملRapid phenotypic antimicrobial susceptibility testing using nanoliter arrays.
Antibiotic resistance is a major global health concern that requires action across all sectors of society. In particular, to allow conservative and effective use of antibiotics clinical settings require better diagnostic tools that provide rapid determination of antimicrobial susceptibility. We present a method for rapid and scalable antimicrobial susceptibility testing using stationary nanolit...
متن کاملRapid colorimetric assay for antimicrobial susceptibility testing of Pseudomonas aeruginosa.
A colorimetric assay based on the reduction of a tetrazolium salt [2,3-bis[2-methyloxy-4-nitro-5-sulfophenyl]-2H-tetrazolium-5-carboxanilide (XTT)] for rapidly determining the susceptibility of Pseudomonas aeruginosa isolates to bactericidal antibiotics is described. There was excellent agreement between the tobramycin and ofloxacin MICs determined after 5 h using the XTT assay and after 18 h u...
متن کاملSelf-assembled magnetic bead biosensor for measuring bacterial growth and antimicrobial susceptibility testing.
Bacterial antibiotic resistance is one of the major concerns of modern healthcare worldwide, and the development of rapid, growth-based, antimicrobial susceptibility tests is key for addressing it. The cover image shows a self-assembled asynchronous magnetic bead rotation (AMBR) biosensor developed for rapid detection of bacterial growth. Using the biosensors, the minimum inhibitory concentrati...
متن کاملRapid Sensor Based Technology: A Novel Tool for Direct Antimicrobial Susceptibility Testing in Urinary Tract Infection
Urinary Tract Infection (UTI) is the second most common infectious disease in humans. Increasing antimicrobial resistance emphasizes the urgent need for quick and reliable diagnostic tests for evidence based antibiotic use/therapy. Increasing trend in resistance to common antibiotics used for treatment of UTI due to polymicrobial infection as opposed to monomicrobial infection makes it importan...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0148864